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Geographical distribution was defined by the countries or regions where the studies were conducted

Rich in antioxidants-VITAMIN C, protects the skin from external factors such as UV rays, keeps the skin elastic and firm, leaving it smooth and revitalised, and works together with glutathione to give an instant radiance to dull and dry skin

Semaglutide drug monograph, BNF

This review highlights the unique potential of phytochemicals to advance the treatment of IC, offering opportunities to move beyond traditional therapies

Unlike topical treatments, IV therapy for skin lightening delivers the antioxidant directly into the bloodstream, allowing for better absorption and more effective results

However, other MC4R-selective agonists demonstrated no pressor effects in the clinic (101)