Ben: As you reflect back on the last 35 years, I was thinking before the episode of making the comment, you've had a one-in-a-million career, but I think that would undersell what has happened because that would mean that there are 7000 equivalently impactful careers in the world, which there are not
However, clinical trials so far have not shown clear benefit of GLP-1 RAs in HF
Despite these differences at the ligand-binding level, the intracellular face of the orforglipron-activated receptor closely resembles the peptide-activated state
Mild water retention or facial flushing shortly after administration
No because celebs who don't need it are using diabetes medication
Changes are happening in your body, and your hormones are triggering that change to happen