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While these agents are still under investigation, they underscore a fundamental shift: obesity pharmacotherapy is moving beyond single-hormone mimicry toward integrated, multi-system approaches that more closely mimic the bodys complex physiology of weight regulation.

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Additionally, patients should be informed that insurance coverage for compounded medications is often limited or unavailable, and that once brand-name products are no longer in shortage, continued use of compounded versions may not be appropriate or legal under FDA regulations

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