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Genetic Engineering of Resident Bacteria in the Gut Microbiome

The disorder is accompanied by a spectrum of serious long-term complications that can profoundly impair quality of life and place an immense strain on healthcare resources

These peptides have gained great attention as a potential weight loss solution

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Several examples, such as Nutlin-3, an inhibitor of the p53:MDM2 interaction 43 , ABT-263/Navitoclax, an inhibitor of BCL-2 family protein interactions 44 , and JQ1, which disrupts complexes of BRD4 with acetylated histones 45 , indicate that this is in principle achievable

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