The effects of GLP-1s increase postprandial insulin secretion from pancreatic -cells, suppress glucagon secretion from -cells, slow gastric emptying, and reduce appetite (Gross)
Some evidence suggests GLP-1 might also affect reward pathways in the brain related to food cravings and the pleasure response to eating
The doses of these drugs used with cells were based on previous data [34,35,36]
I wasnt expecting a dramatic overnight change
Parker VER, Robertson D, Wang T et al (2020) Efficacy, safety, and mechanistic insights of cotadutide, a dual receptor glucagon-like peptide-1 and glucagon agonist
The TRIUMPH-4 trial data showing improved pain scores and metabolic markers alongside weight loss underscores that the benefits of these peptides extend well beyond the number on a scale