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175-181 The finding that the administration of all-trans retinoic acid (ATRA) in elastase-induced emphysema in rats reversed the emphysematous changes, 182 suggested that ATRA might be a beneficial therapy for patients with emphysema

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However, at 50 g/mL, partial DNA degradation was still observed, while the 200 g/mL treatment showed a mild increase in DNA fragmentation, consistent with its higher necrosis rate

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