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Empagliflozin in Heart Failure: Notably, empagliflozin has demonstrated efficacy in treating heart failure, including in patients with a preserved ejection fractiona condition where the heart muscle contracts normally but the ventricles do not fill with enough blood

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The inhibition of SIRP- CD47-SHP-1 axis by using CD47 antagonist, under clinical evaluation, leads to SnCs elimination and maintain the homeostasis of tissues

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