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In contrast, cuproptosis-C1 tumors were characterized by an abundance of T helper cells, central memory T (Tcm) cells, and Th2 cells, alongside elevated expression of immune-checkpoint moleculesa profile that may be associated with immune exhaustion and potentially greater responsiveness to immune-checkpoint blockade (ICB), though this remains to be functionally validated

The trade-off is dosing frequency

N Engl J Med, 384(11), 989-1002 Media Contact: Marcie Kinzel [email protected] www.ivimhealth.com

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The pQCT findings hint that the increase in cortical BMC might be due to an expansion in the cross-sectional bone area

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