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Acetyl Hexapeptide-8 (Argireline) is a 6-amino-acid peptide that mimics the N-terminus of SNAP-25 and inhibits the release of acetylcholine at the neuromuscular junction in muscle adjacent to dermis

Other studies revealed higher levels of itaconate and metabolites such as p -cresol sulfate, p -cresol glucuronide and phenylacetyl-L-glutamine in PD patients than in controls, suggesting potential alterations in inflammatory responses [254, 255]