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Most side effects are minimal and mild

Do not double the dose to catch up

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Because NNMT occupies a central position within nicotinamide methylation pathways, it has become an important target for investigations involving enzyme regulation, methyl-donor utilization, cofactor-associated signaling networks, and methyltransferase pharmacology

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But AOD 9604 makes those efforts more effective at actually burning fat rather than just losing weight (which often includes muscle)