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Tirzepatide added a second hormone target (GIP) to make it a dual agonist, and thats why it outperformed semaglutide in head-to-head trials
***12 mg requires 3 vials (15 mg total in 3.0 mL)
Tirzepatide produced greater A1c reductions in the SURPASS-2 head-to-head trial, making it the stronger option for glucose control
Semaglutide (the generic name for Wegovy) is a part of the GLP-1 receptor agonists, which marked a major advancement in the class of drugs used to treat type 2 diabetes
But in rare cases, this slowdown becomes so severe that the stomach essentially stops emptying altogether
Journal of cardiac failure
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