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Pregnant and breastfeeding women should consult their doctors before starting on a supplementation regimen with L-Carnitine / Levocarnitine + Vitamin E

Research shows NAMPT levels drop with age in several tissues: Adipose tissues Skeletal muscle Retinal pigment epithelial cells Certain brain regions The body's NAMPT levels in extracellular vesicles also decrease with age in both rodents and humans

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doi: 10.1007/s13311-023-01376-2 15 Meyer-FiccaMKirklandJB

Caffeine is the obvious culprit