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The direct group is created by SOD, glutathione peroxidase (GPX), catalase (CAT), and peroxiredoxins (PRDXs)

The half-life spans approximately six to eight days, supporting once-weekly subcutaneous administration

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Proper application and consistency help ensure gradual and visible improvement in uneven tone, especially on thicker skin areas such as knuckles, joints, heels, and toes

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Along the same line, Shi et al