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Excessively consuming such diets not only directly affects energy metabolism in liver, but also increases the concentration of TMAO in plasma, which promotes the development of MAFLD by affecting bile acid metabolism, unfolded protein response, and oxidative stress

Parkman HP, Hasler WL, Fisher RS

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Study design & population Using an active-comparator new-user cohort design [31, 32], we emulated three hypothetical active-controlled randomized trials comparing SGLT2 inhibitors, injectable GLP1 receptor agonists, and DPP4 inhibitors pairwise

Wait at least 60 minutes after eating before injecting, and try to avoid food for about an hour afterward

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