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Furthermore, retatrutide has demonstrated a remarkable ability to reduce liver fat content by up to 86% in individuals with metabolic dysfunction-associated steatotic liver disease (MASLD), and shows promise in mitigating other cardiovascular risk factors

Novo Nordisk, the maker of these weight-loss drugs, does not include warnings about the increased risk of gastroparesis/stomach paralysis (frozen stomach) for people who consume the medications or receive GLP-1 RA treatments

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Most published data involve earlier-generation GLP-1 agonists such as liraglutide, with emerging case series and small studies examining semaglutide and tirzepatide in post-bariatric patients

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