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Second, the successful clinical translation of SFN depends fundamentally on overcoming the substantial interindividual variability in its bioavailability and metabolism

WT-CD, n = 10 mice

ACS Medicinal Chem

doi:10.1016/j.bbamcr.2016.01.023 Zamani M, Pahlavani N, Nikbaf-Shandiz M, et al

Benefits: Always using fresh peptides No worry about degradation Can adjust doses without wasting partially-used vials Trade-off: Slightly more frequent mixing (minor inconvenience for better quality)

The incremental test started with a power output of 95 watts, and increased by 35 watts every three minutes until conclusion of the test (20)