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Inhibiting excessive inflammation at the injury site, reducing further damage to myofibers by inflammatory factors, and creating a favorable microenvironment for muscle repair
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Primary applications include the areas below
Interestingly, when transferring iNOS deficient (Nos2 -/- ) or wild-type bone marrow cells into irradiated recipient mice followed by Lewis lung carcinoma establishment, mice reconstituted with NOS2-deficient bone marrow cells had fewer M1 and similar numbers of M2 macrophages than mice reconstituted with bone marrow from wild-type mice
They are all potential regulators for ferroptosis, and whether the mechanisms involved in liver protection are related to the ferroptosis pathway that ultimately led to the regulation of NAFLD should be further explored in works