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Additionally, some independent factors, such as hypoxia, can further aggravate lipotoxic effects

290:486-494 [PubMed: 12876091] 135

45 Interestingly, overall proportion of patients experiencing at least 1 adverse event was similar across treatment groups

Choosing between the two depends on individual goals, treatment areas, and tolerance for side effects

Abnormal mitochondrial function can lead to an increased calcium uptake by the cells, the excessive production of free radicals and decreased antioxidant protection

The physics of oral peptide delivery fundamentally preclude the sustained-release strategies that succeed with small molecules