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Symptoms typically appear in early childhood, though diagnosis can occur later, especially in milder cases

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Caspases can serve different roles in the apoptotic cascade: some act as initiators (e.g., caspase-8, caspase-9), while others function as effectors (e.g., caspase-3, -6, -7), ultimately executing apoptosis by cleaving essential cellular proteins [159]

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Electrodes are placed on the body or an internal probe is used to measure muscle tension and relaxation