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coli [73] and Rhizobium tropici [74] cells from acid challenge by regulation of gated potassium export channels KefB and KefC, restricting transport of K + ions and thus maintaining the cytoplasmic pH

doi: 10.7759/cureus.88647

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So, pharmaceutical companies started investigating the use of GLP-1s for weight-management purposes, and the first GLP-1 weight-loss drug, Saxenda (liraglutide), was approved by FDA in 2014 (it was previously approved to treat diabetes under the name Victoza)

The 2.5 mg dose is the lowest manufactured tier