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This review has delineated the bidirectional metabolic crosstalk that fuels a vicious cycle of escalating disability

An article outlining the effectiveness of GLP-1RAs on obesity

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doi:10.7150/ijms.11811

A meta-analysis in Scandinavian Journal of Medicine and Science in Sports confirmed that energy deficiency impairs resistance training gains in lean mass, and that individuals performing resistance training to preserve lean mass during weight loss should avoid energy deficits greater than 500 kcal/day (Murphy & Koehler, Scand J Med Sci Sports, 2022)

It's also ideal for those with obesity and related metabolic conditions