MSM, as a source of sulfur, and magnesium are essential for the body's own glutathione production, as are selenium and B vitamins, which are closely linked to glutathione metabolism
Thus, it seems that DSIP may indeed play a role in altering physiology in preparation of the body for sleep, as some of it effects occur before neurological and behavioral signs of sleep
Glycine: A precursor for important metabolites like glutathione, this antioxidant and anti-inflammatory also helps regulate the immune system
doi: 10.1016/j.phymed.2022.154640 117 ZhanWRuanBDongHWangCWuSYuHet al
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A retrospective chart review by Lee et al