glp-1 alzheimer's improves the neuronal supportive ability of astrocytes in disease by regulating mitochondrial dysfunction via the cAMP/PKA pathway Potential Role of Glucagon-like Peptide-1

and the replacement of norleucine with a non-ot-amino acid -aminobutyric acid (GAB A)

In addition, GA markedly elevated the expression of TIMP-1 and attenuates the TIMP-2 expression in ISO-induced rats

It is vital for a plethora of bodily functions, including but not limited to, combating oxidative stress, supporting the immune system, and aiding in the detoxification process

These enzymes include heme oxygenase-1 (HO-1), which degrades heme and exhibits antioxidant and anti-inflammatory effects, NAD(P)H:quinone oxidoreductase 1 (NQO1), which aids in quinone detoxification, and glutamate-cysteine ligase modifier subunit (GCLM), which is crucial for glutathione synthesis

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Neurochemical dissection of synaptic pathology in Alzheimer's disease Int Psychogeriatr 1998