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Low PI3K activity induces BAX expression, which subsequently releases cytochrome c from mitochondria into the cytosol, thereby activating caspase-3 (68)

Nausea Nausea is the most commonly reported side effect , affecting about 46.6% of patients in the OASIS 4 trial, compared to 18.6% on placebo

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S., Aletaha, D., Koeller, M., Weisman, M

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