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A direct detrimental incretin effect on the central nervous system could also be hypothesized and susceptible people receiving GLP-1 RAs may, in some circumstances, experience a worsening of hedonic tone predisposing psychopathology and/or self-harm ideation and/or other aspects of suicidality

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Timing exercise around the ODT dose requires minimal adjustment

Unlike anabolic steroids such as Trenbolone, which act through androgenic pathways, MOTS-c delivers performance benefits via energy regulation rather than muscle-binding hormones

23,36,43 It has also been proposed that increased scrotal fat may impair sperm development through thermal effects