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GLP-1 exerts cytoprotective effects in cell lines (56, 57), but in human islets GLP-1 does not stimulate cell mitogenesis or affect islet size (57, 58)

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Post-Injection Meal Strategy: Hours One Through 48 The first 24 hours after your semaglutide injection is when most appetite suppression and gastrointestinal slowness peak, making small, frequent meals more comfortable than three large ones

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This is known as triple agonist therapy