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Currently, the STAT MASH trial (NCT04679376) is evaluating the efficacy and safety of atorvastatin in MASH with histological criteria

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Studies have shown that high concentrations of BCAAs (20 mM) can inhibit mitochondrial biogenesis and oxidative gene expression in myotube cells, particularly under insulin-resistant conditions (109)

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However, glutathione comes in various forms, such as oral, topical, and IV injection