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Large clinical trials have not identified bone loss as a significant adverse effect, though the weight loss these medications produce may indirectly affect bone density in some individuals
Ibrahim, S
Questions about practical considerations: What is the titration schedule, and how long before I reach the target dose
The main benefit of these medications is that, in large randomized controlled trials, there is an observed weight reduction of on average 15% over 18 months of use
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directly compared GLP-1 receptor agonists to insulin or sulfonylureas, whereas Chang et al
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