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Effect of hemorrhagic shock on bacterial translocation, intestinal morphology, and intestinal permeability in conventional and antibiotic-decontaminated rats

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5-Amino-1MQ functions as a competitive inhibitor at the nicotinamide substrate site of NNMT, with an IC50 of 1.2 M against human NNMT

This is because studies have reported that the interactions between tetracycline and vitamin B12 can reduce absorption and effectiveness of the antibiotic