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When evaluating our dermatology patients, it is worth considering GLP-1 therapy as a potential contributing factor in patients utilizing these therapies

Teleologically, increased GLP-1 secretion plays a role as an ileal brake to maintain a normal speed of energy metabolism by decelerating gastric emptying and suppressing food intake

This is how drug release kinetics can be altered depending on their solubility and the pH inside and outside the membrane

This is consistent with FY2026 CMS guidance for Z code screening categories

Very rare in the trials and not consistently linked to retatrutide specifically, but a known concern across the GLP-1 family

By helping block melanin production naturally, glutathione helps even out skin tone, reduce the look of dark area, as well as impart a healthy glow to the skin.