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This early appetite suppression is one of the most immediate and noticeable effects, even before the scale shows significant weight loss

Schoenfeld BJ, Aragon AA

(2021) injected PTB-ASOs targeted specifically to astrocytes into the cerebrospinal fluid of mice to inhibit PTBP1 expression, and the immunofluorescence results showed a significant increase in tdTomato- and NeuN-labelled neurons in the hippocampus and cortex of mice