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Even so, moving from this biochemical function to clinical outcomes is not always straightforward: the evidence can be heterogeneous and depends on dose, duration, the population studied and lifestyle variables

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50 M of cisplatin for 48 hours produced a similar degree of OHC loss as 10 M cisplatin for 72 hours

Always inspect the product before administration and discard any vial that appears damaged or has passed its expiry date

Furthermore, to provide clinicians with an up-to-date and clinically useful resource to support their daily practice, we discuss practical strategies for the prevention and management of GI adverse events