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The above results show that GPX4 is upregulated by anticancer therapies in vivo, and GPX4 inhibitors in combination with cisplatin reduced tumour size and increased survival in a mouse model of ovarian cancer

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Urine organic acids commonly showed ethylmalonic aciduria suggesting impaired fatty acid, methionine, and/or isoleucine oxidation [26]

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Consequently, inadequate Zn availability in soil is a main consideration for plant nutrition, resulting in a significant loss in production and grain nutrient content

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