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To this end, further work is needed to address whether increasing alpha-cell PC1/3 expression can shift alpha-cell proglucagon processing to favor GLP-1 production over glucagon, thereby mitigating the metabolic consequences of hyperglucagonemia

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[DOI] [PMC free article] [PubMed] [Google Scholar] 67.Thulin P, Nordahl G, Gry M, Yimer G, Aklillu E, Makonnen E, et al