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Immune Support: Strengthens defenses against illness and oxidative damage

In addition, Pycnogenol was shown to lower glycated hemoglobin by 10% in the Pycnogenol group, a significant effect compared to placebo

Specifically, the peptide downregulates inflammatory genes including interleukin-1, tumor necrosis factor-, and nuclear factor-B, while upregulating protective genes such as those encoding antioxidant enzymes, DNA repair proteins, and extracellular matrix components

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