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Discussion 1) In order to determine whether AngIV is involved in the development of Alzheimers, the research team of Sun et al detected the baseline levels of AngIV in both wild type and APP/PS1 mice

The proposed condensation domain C* (CesA_C2) 8 transfers the hydroxy group of D- O -Leu-D-Ala- S -PCP to the thioester carbon of L- O -Val-L-Val- S -PCP to form an ester bond resulting in the PCP-bound tetradepsipeptide L- O -Val-L-Val-D- O -Leu-D-Ala- S -PCP ( DP4 ) 24 , which is subsequently transferred to the serine hydroxy group of the CesB C-terminal TE domain (Fig

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doi: 10.1023/a:1015555023692

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