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While obesity is often described as a simple imbalance in energy homeostasis, where calorie intake exceeds expenditure, this explanation fails to capture the true complexity of the disorder, which reflects a dynamic interplay of genetic and environmental factors that shape energy balance

Treatment satisfaction among participants, as assessed by both DTSQs and DTSQc [23, 24], was generally high at baseline across the seven pooled countries, but treatment with oral semaglutide significantly increased both DTSQs and DTSQc scores at the EOS: estimated mean DTSQs increased by 3.5 points and the estimated mean DTSQc score was 12.2

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