injection of GGsTop at the indicated concentrations (n = 5 animals from one experiment
Why it matters: Ensures the peptide remains structurally intact and stable during shipping and long-term storage
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established a direct neurotoxic action by acetaminophen both in vitro and in vivo in rats at doses below those required to produce hepatotoxicity and suggested that this neurotoxicity might be involved in the general toxic syndrome observed during patient acetaminophen overdose and, possibly, when acetaminophen doses in the upper dosing schedule are used, especially if other risk factors (moderate alcohol drinking, fasting, nutritional impairment) are present
The protective efficacy of NAC (and the other pulmonary therapeutics) was significantly enhanced by the addition of atropine, likely due to inhibition of VX-induced mucous secretion
