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The dual control of insulin secretion by glucose involves triggering and amplifying pathways in beta-cells

doi:10.1016/j.regpep.2004.10.002 284

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doi: 10.1139/cjpp-2017-0683 Summary Keywords GLP-1, Alzheimers disease, blood pressure, DPP-4, non-alcoholic steatohepatitis, signaling pathway Citation Li Q-X, Gao H, Guo Y-X, Wang B-Y, Hua R, Gao L, Shang H-W, Lu X and Xu J-D (2021) GLP-1 and Underlying Beneficial Actions in Alzheimers Disease, Hypertension, and NASH

The incretin/glucagon system as a target for pharmacotherapy of obesity

Others see only a small shift, especially if they are building muscle or if hormonal water retention is present