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After this first work, many other devices have been developed to mimic lungs by different research groups finding application in disease modeling, toxicology studies and drug testing (89, 124129)
Thioredoxin Reductases (TXNRD1, TXNRD2, and TXNRD3) TXNRD1 and TXNRD2 are available in the cytosol and the mitochondria of mammalian cells, are essential for cellular redox balance, and are both highly expressed in the heart
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The resulting correlation between estrogen and antioxidant systems can be used for analyses and discussion
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