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GLP-1: Molecular Mechanisms and Outcomes of a Complex Signaling System

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Prof Stephen Nicholls, the lead of the Australian arm of the Select trial and the director of the Victorian Heart Institute at Monash University, said while the GLP-1 RAs medications were originally developed as diabetes drugs, the Select study excluding diabetic patients showed a new frontier for the drugs in their own right

This protective effect is attributed not only to their influence on systemic metabolism, which safeguards the heart, but also to their direct actions on cardiac tissues

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