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SNAP-8 (acetyl octapeptide-3) and botulinum toxin (Botox) both target the SNARE complex that triggers facial muscle contractions, but through different routes

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This work was supported by the Klingenstein Foundation (E.G.), the National Alliance for Research on Schizophrenia and Depression (E.G) and the NIH (E.G., M.L.M.)

This is crucial in cases where depression is associated with trauma or long-term stress, both of which can lead to neuronal damage