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Rationale, design and baseline characteristics of REMODEL, a mechanism-of-action trial with semaglutide in people with type 2 diabetes and chronic kidney disease

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not therapeutic claims.) Dual GLP-1R/GCGR receptor activation profile studied in published Phase 2 and Phase 3 trials (GLORY program, DREAMS program)

PMID 18594781

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(Peptide Sciences) Importantly: selective removal of senescent cells without significant impact on non-senescent cells