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Challenges include weekly injections, lifelong use needs, side effects like nausea, conservative doctors, and low persistence, as noted by Zerodha's Nithin Kamath and experts urging diet and exercise first
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Will GLP-1s keep me from getting cancer
Pricing changed substantially in late 2025 and 2026
These medications have direct organ protective effects. However, he said more work is now needed to implement the results of the study into clinical practice and improve access to GLP-1 receptor agonists to people who will benefit from them
Source: NEJM 2023 Safety profile: The most common adverse events were gastrointestinal (nausea 58%, diarrhea 39%, vomiting 32% in the 12 mg group)
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