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Discontinue use if redness, itchiness, or irritation occurs

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Chronically stressed people may have lower baseline GLP-1 and reduced tissue sensitivity

PlexusDx's compounded oral semaglutide offers similar effectiveness and works through the same GLP-1 receptor mechanism as brand products

No new safety signals emerged that would halt pursuit of approval

Efficacy plateaus around 6 months for some patients, suggesting that periodic clinical reassessment and possible dose adjustment or formulation change may optimize long-term outcomes