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Thimerosal, a competitive thioredoxin reductase 1 (TrxR1) inhibitor discovered via high-throughput screening

The neurosteroid allopregnanolone protects retinal neurons by effects on autophagy and GABRs/GABA(A) receptors in rat glaucoma models

Berberine ameliorates erectile dysfunction in rats with streptozotocin-induced diabetes mellitus through the attenuation of apoptosis by inhibiting the SPHK1/S1P/S1PR2 and MAPK pathways

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In mouse models that mimicked RBC transfusion and clearance in a clinical setting, the RBC phagocytosis of splenic RPMs increased after rapid transfusion of large amounts of RBCs, but the increase in HO-1 was still insufficient to prevent ferroptosis of splenic RPMs triggered by massive RBC phagocytosis (43)

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