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Overexpression of Drp1 and Atg5 in cardiomyocytes or inhibition of p53 to increase autophagic flux can prevent symptoms such as myocardial hypertrophy and aging [230, 231]

In the ADPKD model, the levels of Met and SAM are increased, which induces the expression of Mettl3

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2021;29(9):1378e926

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