TNF-, another key cytokine elevated in PCOS, sustains this activation loop by upregulating endothelial adhesion molecules (ICAM-1, VCAM-1, and E-selectin), thereby enhancing neutrophil tethering and transmigration
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This provided direct evidence of increased lipid peroxidation in the CF airway and strongly suggested that this elevation is a consequence of the pulmonary inflammation characteristic of CF, rather than a direct, inflammation-independent outcome of the primary CF defect
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Paul Edison, M.D., Ph.D., professor of science from Imperial College London, included 204 patients with mild Alzheimer's disease seen at 24 clinics throughout the United Kingdom
Oct 2003;56(4):362-9
