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The gut-brain axis and systemic inflammation have been implicated in the deposition of amyloid-beta plaques and tau pathology in the brain, both hallmarks of AD (Jia et al., 2024)

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Limited Long-term Data : While short- to medium-term data are compelling, the long-term safety and efficacy profile over decades of treatment remains incompletely characterized

Aug 28 2019;7(9)doi:10.3390/medsci7090089 Lee I, Cooney LG, Saini S, et al

doi: 10.1016/j.ccell.2016.10.009 10 ValadiHEkstrmKBossiosASjstrandMLeeJJLtvallJO

And yes, men will have to deal with the fear of rejection, but as Barrett said, "Welcome to life." Anna Iovine is the associate editor of features at Mashable