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In developed countries, excessive calorie intake and frequent consumption of unhealthy foods, associated with a sedentary lifestyle, have caused an increase in the prevalence of obesity, which in turn predisposes to several non-communicable diseases, such as cardiovascular disease, diabetes, hypertension, and chronic kidney disease [9]
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The weight-drop, midline fluid percussion, and controlled cortical impact models produce focal contusions and, depending on injury severity, may be associated with subarachnoid and intraparenchymal hemorrhages, disruption of the blood-brain barrier (BBB), cortical and subcortical cell loss, and diffuse axonal injury
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